Private suite vacation rentals in Upstate South Carolina

Find and book unique private suite rentals on Airbnb

Top-rated private suite rentals in Upstate South Carolina

Guests agree: these private suite rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guest suite in Taylors

4.96 out of 5 average rating, 261 reviews

*River Park Cottage*~Charming, Quaint & Private

Spacious/completely private guest SUITE w/own garage ATTACHED to house on property. Suited for *2 PEOPLE*~can accommodate 3. Both beds in same room: queen bed & twin Murphy bed. Completely private outdoor space w/firepit. Property backs onto woods w/privacy~almost all 3 sides. Located in safe, quiet neighborhood. 12 min to DT G’ville. This quaint, rustic cottage suite invites you to come enjoy a wonderful getaway! Note*Guests staying longer than 2wks are provided wkly cleanings~Sundays 12-3pm

Mar 24 – 31

$90 per night

Guest favorite

Guest suite in Woodruff

4.96 out of 5 average rating, 193 reviews

Luxurious river front nature retreat on 120 acres

Privacy, luxury and nature-for you! Luxurious apartment in our home (owner-occupied) - on 120 private acres overlooking the Enoree river. Visitors are blown away by the view and the sound of the river. Beautiful walking trail and 2 kayaks available for use. There is a beautiful waterfall located only 600 yards upriver, by kayak. There are bald eagles, turtles, herons, etc.. 15 miles to GSP airport and 21 miles to downtown Greenville and Spartanburg. (No pets, smoking/vaping inside, or guns!)

Oct 9 – 16

$108 per night

Guest favorite

Guest suite in Central

4.97 out of 5 average rating, 143 reviews

Elfwing Carriage House

Bright & comfortable studio apartment located in a quiet family neighborhood in the country, yet minutes to town. We are an easy 15 minute drive to Clemson, less than 5 miles to SWU, 7 miles to Duke Energy. Smart location for the mountains & lakes, visiting colleges, and graduation. Tiger tailgate space available for an additional fee. Hikes, waterfalls, 12 Mile river & Lake Hartwell are nearby. Friendly dogs are fenced or in our home. Come enjoy neighborhood & country living at its finest!

Nov 24 – 29

$101 per night

Guest favorite

Guest suite in Greenville

5.0 out of 5 average rating, 167 reviews

Cozy, Cute & Clean Cottage on Saluda Lake

Stunning lake views from private covered deck with daily western sunsets. Large dock to sit, sun, read or fish. Two kayaks with life vests available to tour the water. Saluda Lake is said to be one of Greenville's best kept secrets. Though a small 331 acre lake, the nearly 2 mile river to the 1920's working dam is great water to boat and fish. 13 mins to main street Greenville; 5 mins to Furman University; 45 mins to Clemson University or Lake Hartwell area. 5 mins to grocery stores.

Oct 3 – 10

$112 per night

Guest favorite

Guest suite in Greenville

4.95 out of 5 average rating, 261 reviews

Downtown Architect's Studio

The Craftsman Studio is a brand new downtown addition to a 110 year old craftsman house. The addition was designed and decorated by a Greenville architect who lives in the main house. The property sits in a historic downtown neighborhood, just 4 beautiful blocks from Main Street. Although it's so close to downtown, the neighborhood is a quiet haven away from urban life. (Although there are kids in the neighborhood which could add some flare/fun noise to your day if you’re staying in.)

Jul 20 – 27

$134 per night

Guest favorite

Guest suite in Campobello

4.98 out of 5 average rating, 244 reviews

Modern Farmhouse Studio

This listing is for a small above the garage studio. Kitchenette has a mini fridge, toaster oven, and coffee maker. This is not a full size kitchen. Does not have a stove. Smart TV for you to sign into Netflix, prime or Hulu. No TV subscription. One queen bed. One full size mattress on the floor in a nook. Fits 2 adults and 2 kids nicely or 3 adults. I provide a few snacks with coffee & tea. Come and enjoy the quiet country life! Our family has 2 outside cats, and 2 indoor/outdoor dogs.

Sep 5 – 12

$81 per night

Guest favorite

Guest suite in Greer

4.87 out of 5 average rating, 596 reviews

The Shalom Suite with pool near DT Greer SC

The Shalom Suite is a perfect spot for a relaxing getaway and this beautiful area! We are conveniently located by: - GSP airport (12 min), - Historic Downtown Greer SC (drive: 2 min, walk: 15 min) - 20 minutes to Downtown Greenville. - Many parks & restaurants (<5 min) You'll enjoy private access, comfy queen bed, ample living area, bathroom (w/ shower), WIFI & pool. We have a kitchenette ready for you w/ a microwave, coffee, mini-fridge and toaster. Pool opens May 1.

Jun 19 – 26

$78 per night

Guest favorite

Guest suite in Chapin

4.98 out of 5 average rating, 456 reviews

LAKE FRONT SWEET - Dog Friendly

In Chapin on beautiful Lake Murray near Dreher Island State Park. Enjoy the view from the patio, relax on our dock, or float in the lake! There's room for your boat and trailer. Lower level of the house is all yours- incl. bedrm, bathrm, living rm & patio. Kitchenette-No stove, but there's a small kitchen sink, gas grill, full size fridge, microwave, toaster, coffee maker & dishes. We provide linens, coffee, cream, sugar. Dog friendly -1 dog if you agree to our rules.

Feb 16 – 23

$108 per night

Guest favorite

Guest suite in Brevard

4.93 out of 5 average rating, 311 reviews

Private guest suite in heart of Cedar Mountain

NO CLEANING FEE Newly constructed private guest suite conveniently located in the heart of Cedar Mountain. This space contains queen bed, tiled shower, kitchenette that includes convection oven, microwave, small refrigerator, coffee pot, tea kettle, small table and chairs, private patio and fire pit(advanced notice required & bring your own wood please). Please note that the only sink is in the kitchenette. Room is very well stocked with coffee, snacks & toiletries.

Jan 8 – 15

$72 per night

Guest favorite

Guest suite in Spartanburg

4.98 out of 5 average rating, 137 reviews

Treetop F.R.O.G.

Treetop FROG, finished room over garage. Separate keyless entry to comfortable loft style apartment less than 2 miles from downtown. House sits on a quiet dead end road backing to a creek. Listen to the water on your private balcony. Sleep deeply on your queen plush top bed. Smart tv moves to the perfect view from entire room. No cable but streaming capabilities for Hulu/Netflix ect. One parking space either down sloped driveway or at top of property

Sep 19 – 26

$67 per night

Guest favorite

Guest suite in Greenville

4.9 out of 5 average rating, 219 reviews

modern lux lakefront suite, 6mi dt GVL

PRIVATE DOCK + LAKEFRONT + JET SKI RENTAL + 6 MILES TO DOWNTOWN GREENVILLE! NY Times #1 AMERICAN CITY! Experience luxury in your serene private suite **located in modern scandinavian-style chalet on Saluda Lake** 6mi downtown Greenville, 5mi Traveler’s Rest, 4mi Furman, 4mi Paris Mtn - Private dock / jet ski paddleboard rental - Private entrance flower-friendly patio - 43” Roku TV - Charcoal grill, fire pit - Blackout blinds

Mar 22 – 29

$87 per night

Guest favorite

Guest suite in Hartwell

4.97 out of 5 average rating, 209 reviews

Relaxing retreat on Lake Hartwell.

NEW IN 2021: New carpet, paint and mattress! Our one bedroom "apartment" has everything you need for a relaxing getaway. Room for air mattresses too. There is swimming, fishing, kayaking, and just plain relaxing here. We are close to hiking and waterfalls. Approximately one hour from UGA or one hour from Clemson for a getaway football weekend. Come enjoy and bring your pets too—they are always welcome!

Apr 14 – 21

$90 per night