House vacation rentals in Seneca
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Top-rated house rentals in Seneca
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Seneca house rentals
House rentals with a pool
Home in West Union
4.95 out of 5 average rating, 137 reviewsSunsets and Siestas -Lake Keowee home near Clemson
Dec 6 – 13
Home in Greenville
5.0 out of 5 average rating, 106 reviewsPalmetto Escape - Pool- Firepit- 6.6 mi DTWN GVL
Nov 17 – 24
Home in Greenville
4.88 out of 5 average rating, 116 reviewsSaluda Splash Home
Sep 16 – 23
Home in Westminster
5.0 out of 5 average rating, 18 reviewsThe Hilltop Hideaway at Lake Hartwell
Nov 27 – Dec 4
Home in Westminster
4.99 out of 5 average rating, 75 reviewsDream Weaver Lakefront• jacuzzi• dog friendly home
Dec 25 – Jan 1
Home in Salem
5.0 out of 5 average rating, 9 reviewsNewly Updated | Lake Keowee | Pool | Amenities
Dec 8 – 15
Home in Walhalla
4.94 out of 5 average rating, 31 reviewsJana Retreat Pool 3 BR/2 Bath
Feb 16 – 23
Home in Seneca
5.0 out of 5 average rating, 11 reviewsKeowee Lakeside with pool for 16
Sep 22 – 29
Weekly house rentals
Home in Seneca
4.97 out of 5 average rating, 120 reviewsLake Hartwell house w/ dock 2 miles from Clemson.
Feb 6 – 13
Home in Central
4.97 out of 5 average rating, 128 reviewsClemson Carriage House | Private Guest House
Jul 1 – 8
Home in Seneca
4.85 out of 5 average rating, 174 reviewsCozy Lake House 5 miles from Clemson w Dock
Sep 11 – 18
Home in Lavonia
4.97 out of 5 average rating, 126 reviewsHygge Hideaway Lake House
Oct 2 – 9
Home in Seneca
4.92 out of 5 average rating, 37 reviewsSouth Cove Bungalow Lake Keowee
Jul 14 – 21
Home in Westminster
4.94 out of 5 average rating, 16 reviewsMountain Road Cottage
Jul 23 – 30
Home in Seneca
5.0 out of 5 average rating, 46 reviewsModern & Cozy Cottage-12 min. from Clemson Uni.
Aug 4 – 11
Home in Westminster
4.92 out of 5 average rating, 88 reviewsShady Rest
Jun 20 – 27
Private house rentals
Home in Fair Play
4.96 out of 5 average rating, 48 reviewsWaterfall Cove - East
Jul 12 – 19
Home in Seneca
5.0 out of 5 average rating, 19 reviewsCozy 3/2 Modern Home in Seneca and Clemson Area
Aug 26 – Sep 2
Home in Seneca
5.0 out of 5 average rating, 54 reviewsLake Hartwell Dock, Lakefront, Kayaks, Clemson 4BR
Oct 5 – 12
Home in Tamassee
5.0 out of 5 average rating, 24 reviewsWhitewater Lake Front Cottage
Oct 2 – 9
Home in Seneca
4.96 out of 5 average rating, 70 reviewsPerfect Lake Hartwell Getaway! Gorgeous Views!
Jan 26 – Feb 2
Home in Walhalla
4.91 out of 5 average rating, 43 reviewsThe Yellow Quilt in Walhalla
Sep 13 – 20
Home in Anderson
5.0 out of 5 average rating, 65 reviewsLakefront dock *Hot tub* Anderson Clemson King bed
Nov 8 – 15
Home in Clemson
5.0 out of 5 average rating, 19 reviewsVaulted Ceilings & Accent Windows--1 mile from CU
May 16 – 23
Quick stats about house rentals in Seneca
Total rentals
30 properties
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Family-friendly rentals
30 properties are a good fit for families
Total number of reviews
1.3K reviews
Nightly prices starting at
$40 before taxes and fees
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