Lake house vacation rentals in South Carolina
Find and book unique lake houses on Airbnb
Top-rated lake house rentals in South Carolina
Guests agree: these lake houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for South Carolina lake house rentals
Waterfront lakehouse rentals
Home in Six Mile
4.95 out of 5 average rating, 57 reviewsLake Keowee Beach Club Cabin
Home in Summerton
5 out of 5 average rating, 95 reviewsCheerful 3 bedroom home on the lake
Home in Westminster
4.99 out of 5 average rating, 100 reviewsDream Weaver: Lakefront• jacuzzi• dog friendly
Home in Chapin
4.94 out of 5 average rating, 83 reviewsLake Murray: Panoramic Views, Kayaks & Hot Tub
Home in Chapin
5 out of 5 average rating, 9 reviewsFamily Ties Lakeside Retreat
Home in Pawleys Island
4.95 out of 5 average rating, 148 reviewsPawleys Island Family Retreat for any Season
Home in Saluda County
4.97 out of 5 average rating, 38 reviewsLil Cricket Lake Cabin Getaway!
Home in Irmo
4.87 out of 5 average rating, 104 reviewsLakefront w pool, dock and pool table, sleeps12
Pet-friendly lake house rentals
Home in Saluda County
5 out of 5 average rating, 36 reviewsLake Murray Paradise/Lakefront/Dock/Wifi/Sunrise
Home in Myrtle Beach
4.91 out of 5 average rating, 163 reviews*Clean *fenced yard * close to intercoastal
Home in Seneca
4.94 out of 5 average rating, 109 reviewsGetaway on Lake Hartwell: Pontoon Rental, Clemson
Home in Bluffton
4.99 out of 5 average rating, 203 reviewsOld Town Bluffton Home + Golf Cart No Cleaning Fee
Home in Easley
4.91 out of 5 average rating, 145 reviewsLarge lake house - 15 min to Downtown Greenville
Home in Myrtle Beach
4.87 out of 5 average rating, 215 reviewsCozy Beach Paradise in Ocean Lakes | Outdoor TV
Home in Modoc
4.93 out of 5 average rating, 109 reviewsIvy’s Escape (water front) at Lake Thurmond
Home in Waterloo
4.88 out of 5 average rating, 42 reviewsStillwater
Private lake house rentals
Home in Gilbert
5 out of 5 average rating, 15 reviewsTranquility
Home in Cross Hill
5 out of 5 average rating, 29 reviewsKristen's Lakeside Retreat with hot tub!
Home in Ridgeway
5 out of 5 average rating, 20 reviewsThe Little House
Home in Seneca
4.87 out of 5 average rating, 15 reviewsCozy Clemson Lake Getaway with Dock Access
Home in Abbeville
4.96 out of 5 average rating, 26 reviewsThe Bird House
Home in Summerton
4.9 out of 5 average rating, 40 reviewsThe Pointe at Goat Island W/Pool, boat ramp & Pier
Home in Waterloo
4.98 out of 5 average rating, 83 reviewsLakefront Home with Hot Tub! Kayaks,SUP's,Fireplace! King beds, PingPong, CornHole!
Home in Eutawville
4.94 out of 5 average rating, 52 reviewsHeated Indoor Pool/Lake Front and Dock
Destinations to explore
- House rentals United States
- Condo rentals South Carolina
- Guesthouse rentals South Carolina
- Rentals with a patio South Carolina
- Boutique hotel rentals South Carolina
- Rentals with an EV charger South Carolina
- Rentals with an accessible height bed South Carolina
- Rentals with an accessible height toilet South Carolina
- Rentals with beach access South Carolina
- Beach condo rentals South Carolina
- Bed and breakfasts South Carolina
- Townhouse rentals South Carolina
- Beachfront rentals South Carolina
- Rentals with outdoor seating South Carolina
- Farmstay rentals South Carolina
- Rentals with a fire pit South Carolina
- Rentals with a washer and dryer South Carolina
- Rentals with a sauna South Carolina
- Aparthotel rentals South Carolina
- Rentals with a kayak South Carolina
- Waterfront rentals South Carolina
- Kid-friendly rentals South Carolina
- Family-friendly rentals South Carolina
- Tiny house rentals South Carolina
- Cabin rentals South Carolina
- Rentals with a home theater South Carolina
- Hotel rentals South Carolina
- Loft rentals South Carolina
- Rentals with pools South Carolina
- Cottage rentals South Carolina
- Bungalow rentals South Carolina
- Rentals with lake access South Carolina
- Ski-in/ski-out rentals South Carolina
- Villa rentals South Carolina
- Beach house rentals South Carolina
- Rentals with breakfast South Carolina
- Serviced apartment rentals South Carolina
- Apartment rentals South Carolina
- Private suite rentals South Carolina
- Smoking-friendly rentals South Carolina
- Resort rentals South Carolina
- House rentals South Carolina
- Hostel rentals South Carolina
- Pet-friendly rentals South Carolina
- Rentals with a hot tub South Carolina
- Fitness-friendly rentals South Carolina
- Rentals with a fireplace South Carolina
- Luxury rentals South Carolina
- Monthly Rentals South Carolina
- House rentals Charlotte
- House rentals Greenville
- Lakehouse rentals Greenville
- Lakehouse rentals Columbia
- House rentals Columbia
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Things to do United States
- Food and drink United States
- Entertainment United States
- Sightseeing United States
- Sports activities United States
- Art and culture United States
- Wellness United States
- Nature and outdoors United States
- Things to do South Carolina
- Art and culture South Carolina
- Sports activities South Carolina
- Nature and outdoors South Carolina
- Food and drink South Carolina
- Sightseeing South Carolina
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes