Guesthouse vacation rentals in Johns Island
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Top-rated guesthouse rentals in Johns Island
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Johns Island guesthouse rentals
Family-friendly guest house rentals
Guesthouse in North Charleston
4.94 out of 5 average rating, 346 reviewsCozy Park Circle, Charleston Guest House
Oct 18 – 25
Guesthouse in Charleston
4.91 out of 5 average rating, 650 reviewsIsland Oasis—Near Downtown
Oct 21 – 28
Guesthouse in Summerville
4.98 out of 5 average rating, 644 reviews★Delightful guest house near historic plantations★
Dec 21 – 28
Guesthouse in Charleston
4.99 out of 5 average rating, 264 reviewsSpacious Daniel Island Apartment
Sep 27 – Oct 4
Guesthouse in Ridgeville
4.82 out of 5 average rating, 213 reviewsPond House Bungalow at Natural Gathering Grounds
Jun 14 – 21
Guesthouse in Charleston
4.93 out of 5 average rating, 317 reviewsCozy Island Cottage
Mar 12 – 19
Guesthouse in North Charleston
5.0 out of 5 average rating, 112 reviewsThe Park Circle Clerestory Studio Guest House
Jul 6 – 13
Guesthouse in Mount Pleasant
4.95 out of 5 average rating, 221 reviewsGreen Garden Studio @greengardenstudio2017
Jul 31 – Aug 7
Guest house rentals with a patio
Guesthouse in Charleston
4.98 out of 5 average rating, 123 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Jan 21 – 28
Guesthouse in Charleston
4.97 out of 5 average rating, 127 reviewsStudio Apartment Minutes to Downtown Charleston
Jan 6 – 13
Guesthouse in Johns Island
5.0 out of 5 average rating, 55 reviewsDriftwood Cottage
Oct 2 – 9
Guesthouse in Charleston
5.0 out of 5 average rating, 13 reviewsGas Light Carriage House James Island
Sep 14 – 21
Guesthouse in Charleston
5.0 out of 5 average rating, 13 reviewsLowcountry Guesthouse
Jul 28 – Aug 4
Guesthouse in Charleston
4.98 out of 5 average rating, 45 reviewsCountry in the City, "The Outback"
Feb 8 – 15
Guesthouse in Charleston
5.0 out of 5 average rating, 75 reviewsLuxury Loft (2 miles from Folly Beach)
Mar 6 – 13
Guesthouse in Goose Creek
4.96 out of 5 average rating, 50 reviewsThe Blue Secret
Jul 17 – 24
Guest house rentals with a washer and dryer
Guesthouse in Charleston
4.98 out of 5 average rating, 245 reviewsDetached Guest Suite
Apr 11 – 18
Guesthouse in Charleston
4.9 out of 5 average rating, 549 reviewsCute, Cozy, Charleston Cottage
Oct 2 – 9
Guesthouse in Charleston
4.99 out of 5 average rating, 207 reviewsRedesigned suite! 12min to city, pet-friendly
Jan 2 – 9
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 222 reviewsCozy Apartment in Mount Pleasant
Dec 26 – Jan 2
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 437 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
Sep 2 – 9
Guesthouse in Charleston
5.0 out of 5 average rating, 144 reviewsThe Guesthouse at Old Orchard
Aug 24 – 31
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 116 reviewsBeach, downtown, Alhambra Hall weddings so close!
Oct 19 – 26
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 249 reviewsUpscale Couple's Escape | Beach & Downtown CHS
Aug 26 – Sep 2
Quick stats about guesthouse rentals in Johns Island
Total rentals
40 properties
Wifi availability
40 properties include access to wifi
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Total number of reviews
5.7K reviews
Nightly prices starting at
$40 before taxes and fees
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- Kid-friendly rentals Johns Island
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- Monthly Rentals Johns Island
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- Rentals with a washer and dryer Johns Island
- Rentals with a fire pit Johns Island
- Rentals with a fireplace Johns Island
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