Guesthouse vacation rentals in Charleston County
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Top-rated guesthouse rentals in Charleston County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for Charleston County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Summerville
4.98 out of 5 average rating, 645 reviews★Delightful guest house near historic plantations★
Guesthouse in Summerville
4.94 out of 5 average rating, 212 reviewsNina's Cottage -Historic Downtown Summerville
Guesthouse in Ridgeville
4.82 out of 5 average rating, 213 reviewsPond House Bungalow at Natural Gathering Grounds
Guesthouse in Charleston
4.91 out of 5 average rating, 650 reviewsIsland Oasis—Near Downtown
Guesthouse in Johns Island
4.98 out of 5 average rating, 240 reviewsPrivate waterfront apt in the oaks
Guesthouse in Summerville
4.87 out of 5 average rating, 749 reviewsNew Loft in Historic Summerville
Guesthouse in North Charleston
4.86 out of 5 average rating, 443 reviewsPark Circle Jungalow Loft
Guesthouse in Charleston
4.99 out of 5 average rating, 264 reviewsSpacious Daniel Island Apartment
Guest house rentals with a patio
Guesthouse in Charleston
4.97 out of 5 average rating, 129 reviewsStudio Apartment Minutes to Downtown Charleston
Guesthouse in Charleston
4.98 out of 5 average rating, 123 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Guesthouse in Johns Island
4.91 out of 5 average rating, 108 reviewsCozy Cottage! 5 mins from Kiawah!
Guesthouse in Goose Creek
4.96 out of 5 average rating, 50 reviewsThe Blue Secret
Guesthouse in Hanahan
4.99 out of 5 average rating, 79 reviewsThe Violet Villa w/ no cleaning fee
Guesthouse in Charleston
4.94 out of 5 average rating, 80 reviewsSpacious 1 bedroom cottage in Avondale
Guesthouse in Charleston
5.0 out of 5 average rating, 13 reviewsLowcountry Guesthouse
Guesthouse in Charleston
4.98 out of 5 average rating, 46 reviewsCountry in the City, "The Outback"
Guest house rentals with a washer and dryer
Guesthouse in Charleston
4.98 out of 5 average rating, 245 reviewsDetached Guest Suite
Guesthouse in Charleston
4.99 out of 5 average rating, 145 reviewsLarge Guesthouse with Private Dock & Marsh Views
Guesthouse in Charleston
4.9 out of 5 average rating, 549 reviewsCute, Cozy, Charleston Cottage
Guesthouse in Charleston
5.0 out of 5 average rating, 218 reviewsJames Island "La Casita" Nestled btw Beach & City
Guesthouse in Charleston
5.0 out of 5 average rating, 144 reviewsThe Guesthouse at Old Orchard
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 437 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 249 reviewsUpscale Couple's Escape | Beach & Downtown CHS
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 258 reviews#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!
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