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Vacation rentals in Panama City

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Panama City

Guests agree: these stays are highly rated for location, cleanliness, and more.

Rental unit in Panamá
Arias Room No. 5
Unique architecture in Casco Viejo, entirely renovated very recently. You have a pool, a rooftop, and your completely private and brand new room. Double bed, designer furniture, tv with Netflix, air conditioning, sheets and towels, shampoo, soap, etc. The building with more history of Casco Viejo, given its name after the first president of the republic in 1903, Tomas Arias, who lived here. Casa Arias is a newly renovated building totally focused on obtaining a one time experience.
$92 per night
Condo in El Cangrejo
Apartment with 2 balconies overlooking Downtown
Everything is nearby in this home. It is strategically located Obarrio, in the heart of downtown Panama. Close to restaurants, bars, shops and supermarkets. One block away you will have the Via Argentina Metro Station where you will find quality nightlife. Two blocks away is the Sortis hotel, which has a Casino. You will have quick access to the roads that take you to get to know the Panama Canal, Amador or Causeway, Old Town and shopping centers such as Albrook mall and Multiplaza.
$58 per night
SUPERHOST
Condo in Marbella
★★★★★Luxury 1 bedroom apt free parking & balcony
Panama is a vibrant, passionate and cosmopolitan city that radiates modernism and opportunity. With its modern creative energy, business opportunity, electric nightlife, unique traditions and extensive natural beauty, it is one of the most exciting capitals to discover. We offer you an exclusive and functional Boutique Apt in the heart of Panama City where fun and enjoyment are just a few steps away!
$66 per night
SUPERHOST

Stay near Panama City's top sights

Photo of Multiplaza Panamá
Multiplaza Panamá147 locals recommend
Photo of Albrook Mall
Albrook Mall132 locals recommend
Photo of Causeway Amador
Causeway Amador67 locals recommend
Photo of Trump International Hotel & Tower Panama
Trump International Hotel & Tower Panama10 locals recommend
Photo of AltaPlaza Mall
AltaPlaza Mall38 locals recommend
Photo of Panama Canal Museum
Panama Canal Museum50 locals recommend

Other great vacation rentals in Panama City

Rental unit in Panamá
COZY COLONIAL APARTMENT
$72 per night
SUPERHOST
Loft in Panamá
Modern aparment Panama! Perfect location.
$31 per night
SUPERHOST
Serviced apartment in Marbella
Cozy apartment | Quartier Marbella D
$80 per night
Rental unit in Panamá
Charming one studio apartment center Casco Viejo
$49 per night
SUPERHOST
Rental unit in Panamá
Charming apartment in the center of Casco CH1
$50 per night
Private room in Panamá
4-A Old City Private Room
$35 per night
Private room in Panama City
4-B Private room Old Town Apartment
$33 per night
Loft in El Cangrejo
Cozy Apartment with Balcony, Downtown-PTY Loft
$56 per night
SUPERHOST
Private room in El Cangrejo
vip-full room, in beautiful-shared-apartment
$24 per night
Private room in Panamá
Ocean 3 Private Room
$23 per night
Condo in Marbella
Apartment overlooking Panama City
$71 per night
Private room in Panamá
Private room with ocean view in Panama
$41 per night
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