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Panama vacation rentals

Book unique homes, vacation rentals, and more on Airbnb

Top-rated vacation rentals in Panama

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Guest favorite
Cottage in Bocas del Toro Province
Rustic cottage-Ocean views/walk to surfing/Jungle
Casa Palmera is located near the only beach to the north/west side of Isla Carenero, with a beautiful ocean view where the sun sets in a secluded and peaceful area. Only a 5 minute walk to the Carenero Surf Break . Restaurants are within walking distance, hike around the island, or use the kayaks and see the beauty. We are 5 minute boat taxi away from the main town of Bocas, but everything you need to make your vacation unforgettable is on this island! Drinking water included.A/C in bedrooms
Nov 2 – 9
$110 per night
4.96 out of 5 average rating, 165 reviews
Guest favorite
Home in Bocas del Toro District
Orange House - Over The Water Rentals
Enjoy golden sunsets across the bay from the Orange House at Over The Water Rentals. Home away from home in a tropical paradise. Relax on your outdoor lounge or explore the bay. The house has snorkel gear, SUP's & kayaks for guests to use for free. Bikes can be rented. Located close to town & airport in a quiet local neighborhood. The house features a king size master bedroom & queen guest room, spacious hot water shower, handmade organic toiletries, fully equipped kitchen & high speed wifi
Aug 3 – 10
$124 per night
4.93 out of 5 average rating, 191 reviews
Guest favorite
Guesthouse in Torio
Torio guesthouse with panoramic view
Our private guesthouse is suspended over the Torio River, on the west coast of the Azuero Peninsula. It is a paradise for hikers, bird watchers, surfers and beach goers. Marked trails with posted maps begin at our place. Hike to a beautiful waterfall, mountain or beach. Photograph birds from the porch. Surf, body board and swim safely (no strong currents). Walk to good restaurants, and a small grocery. Experienced Surfers have Morrillo Beach and Playa Reina. Watch sun and moon rise.
Jun 4 – 11
$67 per night
4.91 out of 5 average rating, 106 reviews

Popular amenities for Panama vacation rentals

Panama house rentals

Guest favorite
Home in Pedasí
3 min to Pedasi, 5 min to the Beach, Private Pool!
Oct 10 – 17
$149 per night
4.93 out of 5 average rating, 106 reviews
Guest favorite
Home in Las Colinas de Caceres de Arraijan
Tropical Haven with Yoga Platform
Sep 29 – Oct 6
$275 per night
4.98 out of 5 average rating, 195 reviews
Superhost
Home in El Valle de Antón
Casa Antares
Oct 13 – 20
$37 per night
4.81 out of 5 average rating, 117 reviews
Guest favorite
Home in El Valle de Antón
Rustic family mountain home - 5 min walk to town!
Apr 27 – May 4
$97 per night
4.93 out of 5 average rating, 112 reviews
Guest favorite
Home in Panamá
Private Studio 10 Min from the airport !
May 9 – 16
$36 per night
4.93 out of 5 average rating, 287 reviews
Guest favorite
Home in Los Algarrobos
New house! 5 min from David on the Boquete highway
Feb 5 – 12
$63 per night
5.0 out of 5 average rating, 115 reviews
Superhost
Home in Bajo Boquete
Secluded Riverfront Home - Boquete area with Pool
Jun 25 – Jul 2
$79 per night
4.81 out of 5 average rating, 105 reviews
Guest favorite
Home in Las Lajas
Casa Inteligente Coronado Pool/Jacuzzi Private
Sep 30 – Oct 7
$115 per night
4.9 out of 5 average rating, 178 reviews
Guest favorite
Home in Bocas del Toro
La Casita Barrbra BnB
Apr 22 – 29
$161 per night
5.0 out of 5 average rating, 5 reviews
Guest favorite
Home in Playa Venao
Casa Samambaia - sea view tropical paradise w pool
Jul 10 – 17
$272 per night
5.0 out of 5 average rating, 13 reviews
Guest favorite
Home in San Carlos
Beach House-Ocean View Rooftop Jacuzzi & Pool
Oct 2 – 9
$226 per night
4.93 out of 5 average rating, 83 reviews
Guest favorite
Home in Panama City
Beautiful house with private pool
May 8 – 15
$135 per night
4.86 out of 5 average rating, 21 reviews

Panama condominium rentals

Guest favorite
Condo in Panama
Patty’s Cozy & Quiet Studio with K-bed in Casco
Aug 9 – 16
$86 per night
4.99 out of 5 average rating, 200 reviews
Guest favorite
Condo in San Carlos District
Punta Caelo beachfront apartment San Carlos
Apr 14 – 21
$140 per night
4.95 out of 5 average rating, 133 reviews
Guest favorite
Condo in Panamá
Spacious Executive Apartment
Sep 22 – 29
$86 per night
4.92 out of 5 average rating, 132 reviews
Guest favorite
Condo in Panamá
Cozy two bedroom apartment
Feb 26 – Mar 5
$78 per night
4.82 out of 5 average rating, 118 reviews
Superhost
Condo in Maria Chiquita
Relaxation by the sea
Nov 23 – 30
$66 per night
4.85 out of 5 average rating, 424 reviews
Guest favorite
Condo in Nueva Gorgona
Beautiful Apartment of Playa-PH Royal Palm-Gorgona
Apr 3 – 10
$80 per night
4.93 out of 5 average rating, 146 reviews
Guest favorite
Condo in Panamá
Excellent complete apartment, Panamá, Panamá
Aug 28 – Sep 4
$188 per night
4.97 out of 5 average rating, 145 reviews
Guest favorite
Condo in Panama City
Park View Luxury Apartment
Feb 27 – Mar 6
$130 per night
4.9 out of 5 average rating, 194 reviews
Guest favorite
Condo in Chame
Exclusive Beachfront apartment 1Hour from Pma City
Jul 16 – 23
$132 per night
4.96 out of 5 average rating, 135 reviews
Superhost
Condo in Panamá
Cozy Unit with Balcony in Santa Ana, Casco Viejo
Jul 28 – Aug 4
$44 per night
4.9 out of 5 average rating, 118 reviews
Guest favorite
Condo in Rio Hato
New Ocean View Condo in Playa Blanca
Dec 7 – 14
$112 per night
4.99 out of 5 average rating, 150 reviews
Guest favorite
Condo in Buenaventura, Río Hato
Modern | Marina View Balcony | Pool | Sleeps 6
Apr 23 – 30
$254 per night
4.9 out of 5 average rating, 105 reviews

Other great vacation rentals in Panama

Superhost
Earthen home in El Cope, Penonome
Beautiful Eco House in Panama
Jul 8 – 15
$185 per night
4.91 out of 5 average rating, 139 reviews
Superhost
Cabin in Panamá Oeste
Cabaña Mirador by Casa Amaya
Aug 27 – Sep 3
$55 per night
4.8 out of 5 average rating, 210 reviews
Guest favorite
Bungalow in Provincia de Chiriquí
Romantic getaway
Jul 13 – 20
$42 per night
4.98 out of 5 average rating, 121 reviews
Guest favorite
Earthen home in playa el arenal pedasi
Earth House Pedasi Experience
Jul 10 – 17
$57 per night
4.96 out of 5 average rating, 113 reviews
Guest favorite
Guesthouse in La Ermita de San Carlos
Sky Cabin/Beaches/Pool/Surf/Digital Nomads
Apr 21 – 28
$32 per night
4.97 out of 5 average rating, 103 reviews
Superhost
Bungalow in Bocas del Toro
Romantic Over the Water Bungalow with Floating Bed
Jun 24 – Jul 1
$150 per night
4.89 out of 5 average rating, 125 reviews
Guest favorite
Bungalow in PA
Great views near hotel facilities
Jun 10 – 17
$101 per night
4.93 out of 5 average rating, 104 reviews
Guest favorite
Cabin in Torio
Cozy open space, unique jungle views, river access
Apr 16 – 23
$102 per night
4.98 out of 5 average rating, 90 reviews
Guest favorite
Apartment in Panamá
Superb Apartment In The Center Of Panama City
Oct 8 – 15
$77 per night
4.96 out of 5 average rating, 55 reviews
Guest favorite
Apartment in Panama City
Stunning views from the clouds!
Jun 17 – 24
$143 per night
4.97 out of 5 average rating, 35 reviews
Superhost
Villa in Bocas del Toro
Bocas del toro - Villa over the water- Bahia Coral
May 10 – 17
$329 per night
4.86 out of 5 average rating, 29 reviews
Guest favorite
Cabin in Chame
Las Nubes En Chica
Sep 18 – 25
$81 per night
4.89 out of 5 average rating, 56 reviews

Your guide to Panama

All About Panama

A narrow isthmus on the southern tip of Central America, Panama is the cultural gateway to South America and the geographical gateway between the Caribbean Sea and the Pacific Ocean. Panama City, its stunning capital city, juxtaposes old-quarter Casco Viejo against the shiny, soaring skyscrapers of the modern district — all surrounded by rolling green hills and vast blue ocean studded with tiny islands. The Metropolitan Natural Park, a wildlife refuge threaded through with hiking trails, is just 10 minutes away from downtown. And Taboga Island, a volcanic enclave featuring a rich array of plants as well as white-sand beaches, is easily reachable via a 30-minute ferry ride.

The terrain rises dramatically from white-sand Caribbean beaches to lush mountain jungles. Near the top of the country, altitude-wise, you’ll find Boquete, home to world-renowned coffee plantations, and the Quetzal Trail, one of Panama’s most scenic hiking trails. Leaving from Volcan Baru National Park, it passes through the Talamanca Mountain Range, where you’ll discover rare tropical wildlife including spider monkeys, tapir, and brightly colored frogs.


The best time to stay in a vacation rental in Panama

The lovely tropical climate makes the prospect of securing a vacation rental in Panama appealing all year long. The drier winter months are ideal for hitting the country’s hiking trails or visiting the beaches. Many of the country’s most significant religious festivals, including Carnaval and Semana Santa (Holy Week), occur in March and April. You’ll want to keep this in mind when booking your Panama house rental if you are headed to a city that hosts a big celebration.

Once Panama’s rainy season starts in May, the sunshine is interrupted with short bursts of heavy rain. It is also usually the quietest time of year for tourism, and you may find yourself alone in the country’s national parks or beaches. That all changes, of course, after the rainy season finishes in November and gorgeous, sunny weather returns.


Top things to do in Panama

Casco Viejo

As the oldest part of Panama City, settled in 1673, Casco Viejo is filled with beautifully restored French and Spanish-style buildings, with a touch of art deco flair. As you stroll down the cobblestone streets, past pastel-colored buildings housing trendy restaurants, upscale bars, and inviting coffee shops, time seems to shimmer between the 19th and 21st centuries. Explore the neighborhood during the day; return after dark for its lively nightlife.

Panama Canal

When the 51-mile Panama Canal opened in 1914, it provided a waterway through Central America and reduced the traveling distance between the Pacific and Atlantic Ocean by 8,000 miles. The impact that this had on global commerce is hard to underestimate. The Pacific mouth of the canal is 26 miles outside Panama City, making it easy to visit this engineering marvel and watch as enormous ships rise and descend through a series of locks.

Bocas Del Toro

Lying close to the border of Costa Rica, this collection of islands is Panama's most popular beach destination. Largely undeveloped, the islands are home to lush tropical rainforest. Great snorkeling and diving opportunities abound in the Isla Bastimentos National Park, which is home to a wide variety of Caribbean coral species as well as (gentle) nurse sharks, crab, and stingrays.

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