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Vacation rentals in Murphysboro

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Top-rated vacation rentals in Murphysboro

Guests agree: these stays are highly rated for location, cleanliness, and more.

Apartment in Murphysboro
2br Guest Suite In Town on 4 Acre Private Estate
Enjoy Southern Illinois from your 2 br home base only 3 blocks from the main street. Have the guest suite all to yourself in a parklike estate, surrounded by the natural wooded beauty of 4 private acres. Bring family or friends, celebrate an anniversary, explore nearby parks, hike, wine taste or bring recreational vehicles for Boating, Motorcycle rides or ATV adventures (space to park your trailer). Even visit SIU Carbondale just a short drive away. There's always adventure in Southern Illinois!
$105 per night
Home in Murphysboro
3bed home w/ 2 car garage. Peaceful setting!
Recently updated 3 bedroom home w/ 2 car garage, washer & dryer and dishwasher. Perfect for families, hunters, fisherman, boaters or just those passing through. Enjoy the country setting with a fire in the fire pit, or grill out on the gas grill on spacious back deck! 4 minutes to Walmart, 7 miles to kinkaid lake marina, 7 miles to siu campus, 7 miles to shawnee wine trail.
$96 per night
Cabin in Murphysboro
Cabin in the heart of Shawnee Hills Wine Trail #1.
This cabin offers a large bedroom/living room combination with sofa and comfortable chairs with a large bathroom and kitchenette with dining area. Check out our other cabin listings at the links below.
$126 per night

Stay near Murphysboro's top sights

17th Street Barbecue31 locals recommend
Cindy B's Cafe3 locals recommend
Cummares8 locals recommend
Molly's Pint Brewpub3 locals recommend
Big Muddy Brewing13 locals recommend
Brews Brothers Taproom6 locals recommend

Other great vacation rentals in Murphysboro

Guesthouse in Carbondale
Homestead Cottage
$90 per night
Cabin in Murphysboro
Cabin in the heart of Shawnee Hills Wine Trail-#2.
$131 per night
Townhouse in Murphysboro
Cozy but big 2 Bd2Bth condo
$78 per night
Private room in Murphysboro
Labrador Lakehouse Large King Bed & Bath
$139 per night
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