House vacation rentals in Little Italy, San Diego

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Top-rated house rentals in Little Italy, San Diego

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite

Home in San Diego

4.9 out of 5 average rating, 191 reviews

Snazzy Spot with yard near beaches and downtown

Welcome to this modern get-away that is as bright and cheerful as a sunny day! You'll be sure to be rejuvenated here after your trips to the nearest beach (only a 15 minute drive) and outings on the town (only 10 minutes by car to downtown). This spot includes a private parking spot and a private yard. Yours to enjoy are a very comfortable queen bed, TV in bedroom, Fast WiFi, and a well stocked kitchenette. There are also two canyon hikes within a 2 minute walk with views of downtown for sunset.

Guest favorite

Home in North Park

4.92 out of 5 average rating, 419 reviews

Quiet & Walkable North Park Getaway | Hot Tub + AC

Enjoy privacy and comfort at this beautiful North Park home in one of San Diego's most charming neighborhoods! It offers an ideal blend of intimacy and convenience - a relaxing retreat, just a short stroll from numerous coffee shops, eateries, microbreweries, Balboa Park, and a swift 10 min drive to the beach! *Pet-friendly *Hot tub + private backyard *Stocked with Avalon Organics/Dr. Bronner's products *Solar-powered *Full kitchen *Coffee from a local coffee roaster *Crib + beach essentials

Guest favorite

Home in Golden Hill

5 out of 5 average rating, 315 reviews

Golden Hill Tree House

The Golden Hill Tree House is an urban oasis hiding in the branches of two mature trees in the heart of San Diego. While you enjoy elevated privacy you can also treat yourself to a soaker tub with double shower heads or settle down in a cozy reading nook to enjoy a good book! You'll also be walking distance to some amazing restaurants and super close to the best of San Diego, including downtown, the beach and the zoo! It's a perfect place to recharge after a long day of business or pleasure!

Guest favorite

Home in Bunker Hill - Park West

4.95 out of 5 average rating, 405 reviews

Admire Harbor Views from the Porch at a City Gem

Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow with Mexican accents and a casual feel.Take a walk into Little Italy for dinner. What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this. Ideal for four or less persons.

Guest favorite

Home in La Mesa

4.99 out of 5 average rating, 134 reviews

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub

Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Superhost

Home in Downtown San Diego

4.9 out of 5 average rating, 613 reviews

#1 LOCATION - Rare Luxury Home in Downtown

***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

Guest favorite

Home in Ocean Beach

4.89 out of 5 average rating, 374 reviews

Ocean Beach Close to all

*We are Covid-19 aware! We have taken extra precautions--sanitizing all surfaces possible, including remote controls, door handles, light switches, etc... after each visit! And we open all the windows to aerate before the next guests! One bedroom granny flat, separate entrance with off street parking for midsize car or smaller. Three blocks to the beach. Located at the edge of downtown OB close to all restaurants and night life. Centrally located to all main San Diego attractions.

Guest favorite

Home in Downtown San Diego

4.98 out of 5 average rating, 233 reviews

Downtown View - 2 Story House Next to Little Italy

Two story house with 2 living rooms; 3 blocks to Little Italy restaurants, bars, & shops. Near Balboa Park, San Diego Zoo, Gaslamp, Waterfront Park & the Harbor. Museums, restaurants, theaters & nature are all nearby. Located in historic Bankers Hill, next to Interstate 5, near the airport and city center. With 2 living rooms, my house is perfect for travelers needing separate space. One parking spot is available. Extra large vehicles will have to park on the street.

Guest favorite

Home in Ocean Beach

4.92 out of 5 average rating, 119 reviews

𖤓 OB Bungalow - Studio Close to all the Action!

This rustic Studio Bungalow is nestled among tropical plants behind a high fence with 2 other cottages. The feeling of privacy is so special right here in the heart of Ocean Beach. Ocean Beach Bungalow is situated just minutes from Newport Avenue with all the eclectic shops, antique stores and incredible restaurants. The neighborhood is quiet, family residential and you can walk just half a block to the end of the street for amazing ocean views from the Cliffs.

Guest favorite

Home in Mission Hills

4.91 out of 5 average rating, 274 reviews

🌟BEST LOCATION🌟 4BR/2BA - WALK to Little Italy 🇮🇹

Updated craftsman style home in THE BEST location! This beautiful house is close to almost everything San Diego has to offer. Only about a mile or two away from Balboa Park, the Zoo, Old Town, The Gaslamp Quarter, The Embarcadero, Hillcrest and just minutes from the airport. WALK to Little Italy in 10 minutes! Beautiful huge backyard with plenty of room to entertain. GREAT for families, or larger groups!! Sleeps 8 comfortably!