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Vacation rentals in Santa Ana

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Ana

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Home in Managua

4.95 out of 5 average rating, 21 reviews

Cozy Townhouse in Managua!

Enjoy a stylish experience at this centrally-located place! This recently renovated house is located in a safe gated residential area, it takes a seven minutes drive to get to Galerias Santo Domingo mall, restaurants, supermarkets, pharmacies and much more. It offers a private and quiet accommodation for vacationers and business travelers. The unit features a comfortable king sized bed, 1 queen and 1 full sized bed. TV and AC, hot water, washer and dryer, work space and a delightful kitchen.

Jul 1 – 8

$95 per night
Guest favorite

Villa in Ticuantepe

5.0 out of 5 average rating, 12 reviews

Casa de Campo, Managua, Ticuantepe

Luxurious Spanish colonial home, with all the comforts you might need to call it home while away, a five acres property in the middle of biggest Pineapple production area of Nicaragua, with a lavish landscape and surrounded by Natural reserve mountains and National parks as the Chocoyero National Park and Volcan Masaya National Park. With your own lighted soccer field and adjacent ranch, private pool, plus a 24 hour care taker, and housekeeping service as requested.

Jun 29 – Jul 6

$225 per night
Guest favorite

Home in Managua

4.99 out of 5 average rating, 74 reviews

Villa Las Palmeras, Estancia de Santo Domingo

Luxurious and Spacious Villa in Premium Location in Residential closed with security 24 hours. Contemporary architecture villa of 600 meters of construction, 5 rooms and 5.5 bathrooms; hot water, Cable TV Digital, Wifi, Wifi, Music Team, 4 Terraces (2 open and 2 covered with TV). Every room equipped with TV, blackout curtains, A/C curtains, and ceiling fans. Other amenities: Wood Oven, BBQ, Pool, Poolhouse, Meditation Magazine Gardens & Nature Exercise Place.

Apr 18 – 25

$425 per night

Popular amenities for Santa Ana vacation rentals

Other great vacation rentals in Santa Ana

Guest favorite

Home in Managua

5.0 out of 5 average rating, 24 reviews

Apt in house/residential, independent, 3 pers.

Jun 18 – 25

$31 per night
Guest favorite

Home in San Rafael

5.0 out of 5 average rating, 33 reviews

Casa Tranqui

Mar 18 – 25

$86 per night
Guest favorite

Apartment in Managua

5.0 out of 5 average rating, 60 reviews

Santo Domingo King bed-one bedroom , fast wifi apt

Sep 12 – 19

$39 per night
Guest favorite

Cottage in Apoyo Lagoon

4.9 out of 5 average rating, 72 reviews

Casa Castillo: Million Dollar View Of Lake Apoyo

Aug 20 – 27

$175 per night
Guest favorite

Cottage in Monte Tabor

4.91 out of 5 average rating, 35 reviews

listing / 8 people

Dec 7 – 14

$162 per night
Superhost

Home in Managua

4.83 out of 5 average rating, 54 reviews

💚🏡“La casita” - Full House - 3 Rooms, Gym, Pool 🏡💚

Aug 14 – 21

$84 per night
Guest favorite

Home in Apoyo Lagoon

4.94 out of 5 average rating, 87 reviews

Luxury Waterfront @ Laguna de Apoyo

Sep 7 – 14

$258 per night
Guest favorite

Home in Managua

5.0 out of 5 average rating, 18 reviews

Casa Mendoza, a nice place to rest.

Jan 20 – 27

$105 per night
Superhost

Home in Managua

4.91 out of 5 average rating, 23 reviews

Well-appointed small home in residential community

Feb 27 – Mar 6

$31 per night
Superhost

Cottage in Laguna De Apoyo, Catarina

4.88 out of 5 average rating, 40 reviews

Rainforest vacation house, Laguna de Apoyo.

Feb 5 – 12

$186 per night
Superhost

Guesthouse in Ticuantepe

4.93 out of 5 average rating, 92 reviews

Nice Vacation Guest House,Managua

Jun 29 – Jul 6

$44 per night
Guest favorite

Home in Managua

4.96 out of 5 average rating, 73 reviews

Cozy residential home 🏡 in Managua. The best!

Jun 4 – 11

$120 per night

Destinations to explore

  1. Airbnb
  2. Nicaragua
  3. Managua Region
  4. Managua
  5. Santa Ana