Vacation rentals in Hannibal

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Hannibal

Guests agree: these stays are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Home in Hannibal

4.92 out of 5 average rating, 236 reviews

Modern 2 Bdr House in Great Neighborhood

This house is close to family-friendly activities, shopping and nightlife. You’ll love this house because of its great neighborhood location and the ambiance. My place is good for families, couples, solo adventurers, and business travelers. Very close proximity to Hannibal YMCA, under 2 miles (less than 5 minutes) from Historical downtown Hannibal, Movie Theater, Hannibal Regional Hospital, Shopping Center and the Mark Twain Cave are all nearby. Located just 30 minutes from Mark Twain Lake.

Jan 23 – 30

$89 per night

Guest favorite

Home in Hannibal

4.97 out of 5 average rating, 34 reviews

Little House in the Hollow

Enjoy a private peaceful setting that is Conveniently located. Large fenced in yard for the kids and/or pets. Also has a 4 person hotub which is available year-round. The house is fully stocked for convenience. The house also has covered parking, outdoor fire pit, BBQ grill a play place for the kids and more. You will be within walking distance of 2 National Landmarks (Mark Twain Cave, Cameron Cave) as well as our Winery and Giftshop. Located just two miles from Hannibal's Historic District.

Oct 24 – 31

$161 per night

Guest favorite

Home in Bowling Green

4.97 out of 5 average rating, 200 reviews

Peaceful Country Cottage

Traveling for work or pleasure? Enjoy a peaceful country view while relaxing on the front porch. This home sits on 14 acres, just off US Highway 61. Guests will see deer roaming in the yard early morning and at night. This rental accommodates families traveling with children or the couple seeking a quiet retreat. Stay here while you visit family and friends in the area. It is a short drive to Vandalia, Louisiana, Hannibal or Mark Twain Lake. (40 Min). About one hour from St. Louis.

Dec 10 – 17

$130 per night

Guest favorite

Home in Palmyra

4.92 out of 5 average rating, 131 reviews

Cozy country 2-bedroom home with a view.

Make some memories at this unique and family-friendly place. Enjoy the view of horses grazing while sipping your morning coffee on the front porch. Drive to historic Hannibal, MO (11 miles). Book a guided farm tour with the owners and/or a riding lesson on one of their many rodeo horses. This house sleeps 6 with a king bed, queen bed, and couch fold-out queen bed. Need more room? (See the other listing for this option). The hostess is right next door to assist with any of your needs!

Feb 18 – 25

$84 per night

Guest favorite

Home in Hannibal

4.98 out of 5 average rating, 56 reviews

Hatton House North St. & N. Main St- 2-6 guest

Your family will be close to everything when you stay at this downtown home on the corner of N. Main St. & North St. Convenient with views of the river and all of Main St from the front porch . Their is a deck over the front porch on the second floor. The bathrooms are complete with shower . Laundry room is convenient with washer and dryer. There is a patio in the back with a table and chairs for dining or just gathering with friends and family. Hosting you will be our top priority.

May 2 – 9

$176 per night

Guest favorite

Home in Hannibal

4.93 out of 5 average rating, 28 reviews

Genevieve’s Federal House

This home is a fully restored 1 story Federal house, which you will have full access to. It is located close to the Mark Twain Boyhood Home, and right off Broadway. The house comes furnished with seating, furniture, and 2 Roku televisions. There are two bedrooms, one bathroom, a dining room, living room, and a kitchen. The home has central air conditioning and heating, washer and dryer, dishwasher, and a beautiful clawfoot cast-iron tub with shower. There is off street parking.

Sep 27 – Oct 4

$163 per night

Guest favorite

Cottage in Philadelphia

4.94 out of 5 average rating, 548 reviews

Frogmore Cottage on 5-acre lake, Enjoy Nature!

Most suited for 2 people but can sleep 6. Enjoy nature… “frogs n more” on this five-acre lake on 25 well-manicured acres. Fabulous sunsets! For a tiny house it has a spacious lower level with vaulted ceiling and upper bedroom loft. Wifi & TV includes Netflix, Amazon, Hulu. Outdoor activity includes hammocks, swimming, boating (canoe, kayaks, john boat). For fishing we have boats, nets & fish-dressing station (bring poles & bait). Please list accurate number of guests when booking.

Dec 10 – 17

$177 per night

Guest favorite

Apartment in Palmyra

4.98 out of 5 average rating, 46 reviews

Apartment at Badass Holler

Unwind and enjoy the peace of staying on a working farm. This “bungalow” is a newly renovated workshop filled with the comfort of home and finished with vintage details from the original owners. You may visit with the farm’s miniature livestock: goats, donkeys, and cows, or wade in the creek or sit outside and look at the stars and listen to the night time noises. (ONE dog 25 pounds or less is allowed for $30 pet fee. MUST leash outside.). No cleaning fee!

Nov 22 – 29

$103 per night

Guest favorite

Home in Hannibal

4.99 out of 5 average rating, 168 reviews

Night at the Twain Museum

Come for an adventure and escape to the 19th Century! Night at the Twain Museum gives travelers an immersion experience into the life of Mark Twain, with a carefully curated collection charmingly presented. Luxury Sleep Number King bed with 65” smart TV. Comfy Casper King is the second bed. Blackout bedroom blinds. Newly remodeled home. New sofa sectional with 65" smart TV. Front & back decks. Close to Main St.

Feb 1 – 8

$199 per night

Guest favorite

Home in Quincy

4.94 out of 5 average rating, 229 reviews

❤️Quincy Quarters❤️

Quincy Quarters is a beautifully restored 1880’s Duplex with modern amenities and all the historic charm. This duplex has been home to families for 140 years. Bring your family and your pet and enjoy 140 years of history. Quincy Quarters is close to Oakley Lindsay Center, Blessing Hospital and Quincy University, it is blocks away from South Park and just a couple minutes from downtown Quincy.

Mar 18 – 25

$93 per night

Superhost

Home in Hannibal

4.88 out of 5 average rating, 17 reviews

Lamb quarters

Relax with the whole family at this peaceful place to stay. Just a few minutes from downtown Hannibal, MO. 2-queen beds. Each bedroom has its own bathroom. One of the bedrooms is in the basement. This charming house offers a comfy living room, a fully equipped kitchen, laundry and outdoor patio area. Perfect for family vacations, romantic getaways, or business trips.

Sep 26 – Oct 3

$112 per night

Guest favorite

Cottage in Hannibal

4.97 out of 5 average rating, 102 reviews

The Rose Cottage in historic downtown Hannibal

Located at the tip of historic Main Street in downtown Hannibal and within easy walking distance of many Mark Twain attractions, restaurants, pubs, shopping, entertainment, etc. At the Rose Cottage, we strive to provide guests with a high quality stay in a cozy, relaxing environment where they can easily enjoy all that downtown Hannibal has to offer.

Oct 6 – 13

$178 per night

Vacation rentals for every style

Get the amount of space that is right for you

Popular amenities for Hannibal vacation rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Stay near Hannibal's top sights

Mark Twain Cave and Cameron Cave19 locals recommend

Center Street Landing - Mark Twain Riverboat9 locals recommend

Mark Twain Dinette: Maid-Rite Restaurant and Diner11 locals recommend

Mark Twain Brewing Company13 locals recommend

Mark Twain Boyhood Home and Museum23 locals recommend

Java Jive16 locals recommend

Other great vacation rentals in Hannibal

Guest favorite

Home in Hannibal

4.97 out of 5 average rating, 59 reviews

Molly’s Riverview Retreat

Jul 29 – Aug 5

$360 per night

Guest favorite

Cabin in Camp Point

4.99 out of 5 average rating, 80 reviews

Oakbrook Akers Lakeside Cabin Retreat

Jul 11 – 18

$120 per night

Guest favorite

Home in Hannibal

4.98 out of 5 average rating, 50 reviews

The Quarry House

Jan 22 – 29

$504 per night

Superhost

Home in Hannibal

5.0 out of 5 average rating, 4 reviews

Riverfront Retreat

Jun 15 – 22

$361 per night

Guest favorite

Home in Hannibal

4.96 out of 5 average rating, 27 reviews

Mississippi Sunrise

Mar 5 – 12

$191 per night

Guest favorite

Farm stay in Coatsburg

4.98 out of 5 average rating, 40 reviews

Your Getaway in the country!

May 26 – Jun 2

$131 per night

Superhost

Apartment in Hannibal

4.81 out of 5 average rating, 26 reviews

Huck Finn: Studio

Sep 11 – 18

$150 per night

Guest favorite

Home in Hannibal

4.91 out of 5 average rating, 33 reviews

Cozy 3 bed/2 bath home with off street parking

Mar 25 – Apr 1

$166 per night

Show all

Quick stats about vacation rentals in Hannibal

Total rentals
80 properties
Rentals with dedicated workspaces
30 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
3.3K reviews
Nightly prices starting at
$40 before taxes and fees

Frequently Asked Questions

Are there vacation rentals with a dedicated workspace in Hannibal?
Yes! Work meets play with ease at over 30 vacation rentals in Hannibal featuring dedicated workspaces. Stay connected and productive in your home away from home.
Do apartment rentals in Hannibal have wifi?
Absolutely! We offer over 10 apartment rentals with wifi in Hannibal. Enjoy a tailored experience with all the comforts you desire.
Are there pet-friendly vacation rentals in Hannibal?
Four-legged friends are welcome in Hannibal. Choose from more than 10 vacation rentals for guests traveling with pets.
Do house rentals in Hannibal have a bbq area?
Absolutely! We offer over 10 house rentals with a bbq area in Hannibal. Enjoy a tailored experience with all the comforts you desire.
Are there family-friendly vacation rentals in Hannibal?
Hannibal has more than 40 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.
What are the most popular amenities for Apartment Rentals in Hannibal?
Enhance your stay in our Apartment Rentals with the most popular amenities: over 10 homes with air conditioning, over 10 homes with wifi, and more. Indulge in the ultimate retreat, tailored to your preferences.
How much does it cost to stay in house rentals in Hannibal?
Experience the best of Hannibal with our house rentals, starting at about $40 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Do apartment rentals in Hannibal have air conditioning?
Absolutely! We offer over 10 apartment rentals with air conditioning in Hannibal. Enjoy a tailored experience with all the comforts you desire.

Vacation rentals in Hannibal

Top-rated vacation rentals in Hannibal

Vacation rentals for every style

Hotels

Unique stays

Homes

Popular amenities for Hannibal vacation rentals

Stay near Hannibal's top sights

Other great vacation rentals in Hannibal

Home in Hannibal

Cabin in Camp Point

Home in Hannibal

Home in Hannibal

Home in Hannibal

Farm stay in Coatsburg

Apartment in Hannibal

Home in Hannibal

Quick stats about vacation rentals in Hannibal

Total rentals

Rentals with dedicated workspaces

Pet-friendly rentals

Family-friendly rentals

Total number of reviews

Nightly prices starting at

Frequently Asked Questions

Are there vacation rentals with a dedicated workspace in Hannibal?

Do apartment rentals in Hannibal have wifi?

Are there pet-friendly vacation rentals in Hannibal?

Do house rentals in Hannibal have a bbq area?

Are there family-friendly vacation rentals in Hannibal?

What are the most popular amenities for Apartment Rentals in Hannibal?

How much does it cost to stay in house rentals in Hannibal?

Do apartment rentals in Hannibal have air conditioning?

Destinations to explore